ea0032p513 | Endocrine tumours and neoplasia | ECE2013
Verdelli Chiara
, Varia Valentina
, Meregalli Mirella
, Terranegra Annalisa
, Guarnieri Vito
, Scillitani Alfredo
, Passeri Elena
, Vocentini Leonardo
, Ferrero Stefano
, Spada Anna
, Corbetta Sabrina
Cancer cells and embryonic stem cells share many key biological properties and have common genetic signature: transcription factors regulating self-renewal and differentiation have been found expressed in human cancer cells. We focused our attention on TBX1, the gene involved in 22q11.2 microdeletion/DiGeorge syndrome, which is involved in heart, thymic and parathyroid cells differentiation.Real-time PCR, western blot and immunohistochemistry de...